Vol. 8, №2, 2016


Alexander R. Zaritsky, Galina V. Zaytseva, Marina N. Kirichenko

Lebedev Fizichesky Institute, Russian Academy of Sciences, http://www.lebedev.ru
119991 Moscow, Russian Federation
zaritsky@sci.lebedev.ru, zaytseva-gv@yandex.ru, maslova_marina@mail.ru
Vladimir I. Grachev
Kotelnikov Institute of Radio Engineering and Electronics, Russian Academy of Sciences, http://www.cplire.ru
125009 Moscow, Russian Federation

Received 16.11.2016
Abstract. In this paper we consider a well-known phenomenon in the life and the evolutionary development of animal cells - the presence in their cytoplasm gel. Described the evolution of the gel appearance with the dynamics of sol-gel phase transitions. Substantiated the main function of the gel in the cytoplasm - providing intensification of the energy metabolism of cells. Shown the role of the gel in the infrastructure of the cell and its compartments, the relationship of the gel and the cytoskeleton, promoting transmembrane exchange of cell with the environment. Shown the role of gel channels in the logistics of water flows and active substances in the cytoplasm, in the regulation of metabolic mechanisms, in particular, in the regulation of the cytoplasm dehydration modes - of sporulation in unicellular organisms and of the drying of human dermal cover in the norm and in various pathologies.

Keywords: cytoplasm, sol, gel, structured water, energy metabolism, cytoskeleton, gel channels, waterways, dehydration mechanisms

PACS: 87.32.Kg

Bibliography – 34 references

RENSIT, 2016, 8(2):215-223 DOI: 10.17725/rensit.2016.08.215
  • Huxley TH. On the Physical Basis of Life. Fortnightly Review, 1869, 5:129.
  • Heilbrunn LV. The dynamics of living protoplasm. New York, Academic Press, 1956, 336 p.
  • Attwood TK, Campbell PN, Parish JH, Smith AD, Stirling JL, Vella F, Cammack R (eds). Oxford dictionary of biochemistry and molecular biology. Oxford, UK, Oxford University Press, 2006, 736 p.
  • Alberts B, Bray D, Lewis J, Raff M, Roberts K, Watson JD. Molecular Biology of the Cell. Vol. 2. NY-London, Garland Publ., 1989, 541 p.
  • Lyuin B, Cassimeris L, Lingappa VR, Plopper G. (eds.). Cells. Sudbury, Jones&Bartlett Publ., 2007, 951 p.
  • Goodacre R, Vaidyanathan S, Dunn WB, Harrigan GG, Kell DB. Metabolomics by numbers: acquiring and understanding global metabolite data. Trends in biotechnology, 2004, 22(5):245-252.
  • Bright GR, Fisher GW, Rogowska J, Taylor DL. Fluorescence ratio imaging microscopy: temporal and spatial measurements of cytoplasmic pH. The Journal of cell biology, 1987, 104(4):1019-1033.
  • Verkman AS. Solute and macromolecule diffusion in cellular aqueous compartments. Trends in biochemical sciences, 2002, 27(1):27-33.
  • Weiss JN, Korge P. The cytoplasm: no longer a well-mixed bag. Circulation research, 2001, 89(2):108-110.
  • Ellis RJ. Macromolecular crowding: obvious but underappreciated. Trends in biochemical sciences, 2001, 26(10):597-604.
  • Luby-Phelps K. Cytoarchitecture and physical properties of cytoplasm: volume, viscosity, diffusion, intracellular surface area. International review of cytology, 2000, 192:189-221.
  • Persson E, Halle B. Cell water dynamics on multiple time scales. Proceedings of the National Academy of Sciences of the United States of America, 2008, 105(17):6266-6271.
  • Ling GN. Life at the Cell and Below-Cell Level: the Hidden History of a Fundamental Revolution in Biology. New York, Pacific Press, 2001, 373 p.
  • Pollack GH. Cells, Gels and Motors Life. The New Unifying Approach to Cell Function. Ekaterinburg, Tokmas-Press, 2009, 386 p.
  • Zaguskin SL, Nikitenko AA Ovchinnikov SA, Prokhorov AM, Savranskii VV, Degtyarev VP, Platonov VI. About period range microstructures of living cells hesitation. Dokl. Academy of Sciences of the USSR, 1984, 277 (6):1468-1471.
  • Pollack GH. The Fourth Phase of Water: Beyond Solid, Liquid, and Vapor. Seattle, Ebner & Sons Publ., 2013.
  • Suzuki D, Kobayashi T, Yoshida R, Hirai T. Soft actuators of organized self-oscillating microgels. Soft Matter, 2012, 8(45):11447-11449, DOI: 10.1039/C2SM26477C.
  • Giudice E. Del, Tedeschi A, Vitiello G, Voeikov V. Coherent structures in liquid water close to hydrophilic surfaces. Journal of Physics: Conference Series, 2013, 442(012028):1-5.
  • Voeikov VL. Active oxygen, water, and organized processes of life. Proc. II Intern.Congress "Low and super-low fields and radiations in biology and medicine" Saint-Petersburg, Tuscarora, 2000, p. 1-4.
  • Pershin SM, Bunkin AF. Observation of temperature evolution of relative concentration ortho/para spin-isomers H2O by four-photon spectroscopy. Laser Physics, 2009, 19(7):1-5.
  • Zaritskii AR, Grachev VI, Vorontsov YuP, Pronin VS. Energeticheskie aspekty abiogeneza v atmosfere na nanokaplyakh uglevodorodnogo aerozolya [Energy aspects of abiogenesis in the atmosphere on hydrocarbon aerosol nanodroplets]. Radioelektronika. Nanosistemy. Informatsionnye tekhnologii (RENSIT), 2013, 5(2):105-125 (in Russ.).
  • Zaritskii AR, Grachev VI, Vorontsov YuP, Pronin VS. Abiogenez na etape perekhoda iz atmosfery v vodnuyu sredu: ot vesikul k protokletkam [Abiogenesis transition from the atmosphere into the hydrosphere: from vesicles to protocells]. Radioelektronika. Nanosistemy. Informatsionnye tekhnologii (RENSIT), 2014, 6(2):221-231; DOI: 10.17725/RENSITe.0006.201412f.0221 (in Russ.).
  • Zaritskii AR, Pronin VS. Biophysics major modes of cellular metabolism. Functional cell modes: a state of rest and activity. Bulletin of the Lebedev Physics Institute, 2006, 12:8-18.
  • Zaritskii AR, Pronin VS. Biophysics major modes of cellular metabolism: mode of cell division (mitosis). Bulletin of the Lebedev Physics Institute, 2006, 12:19-27.
  • Zaritskii AR, Grachev VI, Vorontsov YuP, Kirichenko MN, Pronin VS. Anaerobny etap evolutsionnogo razvitiya zhivotnoy kletki [Anaerobic stage of the evolutionary development of animal cell]. Radioelektronika. Nanosistemy. Informatsionnye tekhnologii (RENSIT), 2015, 7(1):87-99; DOI: 10.17725/RENSITe.2015.07.087 (in Russ.).
  • Doolittle WF, Zhaxybayeva O. On the Origin of Prokaryotic Species. Genome Res., 2009, 19:744-756.
  • Lepeschkin WW. My opinion about protoplasm. Protoplasma, 1930, 9:269.
  • Gurvich AG. Problema mitogeneticheskogo izlycheniya kak aspekt molekulyarnoy biologii [The problem mitogenetic radiation as an aspect of molecular biology]. Leningrad, Medicine Publ., 1968, 240 p.
  • Kaznacheev VP, Mikhailova LP. Sverkhslabye izlucheniya v mezhkletochnykh vzaimodeystviyakh [Superlow radiations in cell-cell interactions]. Novosibirsk, Nauka Publ., 1981, 144 p.
  • Burlakov AB, Burlakova OV, Golichenkov VA. Distantsionnye vzaimodeystviya raznovozrastnykh embrionov v'yuna [Distant interaction uneven loach embryos]. DAN, 1999, 368(4):562-564.
  • Burlakov AB, Burlakova OV, Golichenkov VA. Vozmozhnost' izmeneniya individual'nogo biologicheskogo vremeni slabymi elektromagnitnymi izlucheniyami [Ability to change of individual biological time by low electromagnetic radiations]. Proc. V Int. Congress "Weak and super-weak fields and radiations in biology and medicine" (29.6-3.7.09), St.-Petersburg, Russian State Hydrometeorological University Publ., 2009, p. 41-47.
  • Congress Website "Weak and super-weak fields and radiations in biology and medicine", St.-Petersburg, Russia: http://www.biophys.ru/congress-2015.
  • Zaritskii AR, Zaitseva GV, Grachev VI, Kirichenko MN. Elektricheskoe pole v tsitomembrane kak faktor intensifikatsii metabolizma kletok [Electric field in the cytoplasmic membrane as factor for improved cell metabolism]. Radioelektronika. Nanosistemy. Informatsionnye tekhnologii (RENSIT), 2016, 8(1):91-103, DOI: 10.17725/rensit.2016.08.91.
  • Gitai Z. The new bacterial cell biology: moving parts and subcellular architecture. Cell, 2005, 120(5):577-586.

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